Mendel Jacobs MD

Mendel Jacobs, MD: Preventive Cardiology & AI in Medicine

Internal medicine resident at Yale. I write about preventive cardiology and AI in medicine, and build tools that make cardiovascular health easier to understand.

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Your LE8 scoreSample
82/ 100

High cardiovascular health

Nutrition
85
Activity
90
Nicotine
100
Sleep
55
Body size
80
Cholesterol
80
Blood sugar
90
Blood pressure
75
Explore your results with AI

Illustrative preview · not your results

Recent Articles

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How the LDL Reduction Calculator Works: Methods and Evidence

Sep 16, 2026 · Cholesterol & Lipids

Five layers of clinical AI evaluation, from knowledge benchmarks to patient outcomes

How to Evaluate a Clinical AI Tool: The Five Layers

Sep 12, 2026 · AI in Medicine

The evolution of medical AI benchmarks from MedQA to patient outcome trials

How Medical AI Got Graded: The Evolution of Clinical LLM Benchmarks

Sep 12, 2026 · AI in Medicine

OpenEvidence versus ChatGPT for clinical use: what the evidence supports

OpenEvidence vs ChatGPT: Which Should a Clinician Actually Use?

Sep 12, 2026 · AI in Medicine

Physician using ChatGPT for healthcare to summarize clinical notes, labs, medications, and medical evidence

AI in Medicine Review: 6 Stories From August-September 2026

Sep 9, 2026 · AI in Medicine

Sketchy Medical and Anki study guide illustration with Sketchy Micro, Sketchy Pharm, Sketchy Path, and spaced repetition

Best Sketchy Pathology Anki Deck: Conaanaa's SALT Deck

Sep 9, 2026 · The White Coat

What I'm working on

AI in Medicine

Notes from the learning curve: clinical AI, evaluation, safety, workflow design, and tools that might actually help physicians and patients.

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Vital8 and Preventive Cardiology

A place to work through prevention, Life's Essential 8, and the practical tools that can make cardiovascular risk easier to understand.

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The White Coat

Frameworks, worksheets, and honest notes for medical students and residents trying to feel a little less lost on the wards.

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Vital8

Vital8 is a data-informed framework centered on Life's Essential 8, the core factors that shape cardiovascular health and longevity.

Eat BetterBe More ActiveQuit TobaccoSleep HealthManage WeightControl CholesterolManage Blood SugarManage Blood Pressure
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Latest Vital8 Articles

How the LDL Reduction Calculator Works: Methods and EvidenceCholesterol Blood Tests: LDL-C vs ApoB vs Lp(a) vs hs-CRP

Publications

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Association of Rheumatoid Arthritis with Major Adverse Cardiovascular Events Despite Normal Myocardial Perfusion Imaging

American Journal of Preventive Cardiology

Evaluating the Quality of Cardiovascular Disease Information From AI Chatbots: A Comparative Study

PMID: 40821349

Lipoprotein(a): A Review of Risk Factors, Measurements, and Novel Treatment Modalities

PMID: 38415744

Harnessing the Power of AI: A Comprehensive Review of Left Ventricular Ejection Fraction Assessment With Echocardiography

PMID: 38520327

Newsletter

Occasional essays and notes as I learn, write, and build around medicine, prevention, and AI.

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Professional headshot of Mendel JacobsMendel Jacobs on LinkedIn Connect for research updates, writing, and product work in preventive cardiology and AI.