Mendel Jacobs, MD: Preventive Cardiology & AI in Medicine
Internal medicine resident at Yale. I write about preventive cardiology and AI in medicine, and build tools that make cardiovascular health easier to understand.
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Recent Articles
View all postsHigh Blood Pressure and Life Expectancy: What Studies Show
Nov 1, 2026 · Blood Pressure
High Blood Pressure Stages: Know Your Numbers
Nov 1, 2026 · Blood Pressure
How to Check Blood Pressure at Home
Nov 1, 2026 · Blood Pressure
When Is High Blood Pressure an Emergency?
Nov 1, 2026 · Blood Pressure
The Swan-Ganz Catheter: A Practical Guide for Residents
Oct 25, 2026 · The White Coat
ABIM & ITE Board Review: Podcasts, Questions & Anki
Oct 19, 2026 · The White Coat
What I'm working on
AI in Medicine
Notes from the learning curve: clinical AI, evaluation, safety, workflow design, and tools that might actually help physicians and patients.
ExploreVital8 and Preventive Cardiology
A place to work through prevention, Life's Essential 8, and the practical tools that can make cardiovascular risk easier to understand.
ExploreThe White Coat
Frameworks, worksheets, and honest notes for medical students and residents trying to feel a little less lost on the wards.
ExplorePublications
View all publicationsPharmacologic Stress Myocardial Perfusion Imaging with SPECT and PET in Liver Transplant Candidates: Physiologic Limitations, Current Evidence, and Future Directions
Current Cardiology Reports · 2026
This review examines how cirrhosis affects SPECT and PET myocardial perfusion imaging in liver transplant candidates. It explains the limitations of relative perfusion imaging and the potential value of quantitative PET, while emphasizing that transplant-specific thresholds and effects on clinical outcomes remain unvalidated.
Association of Rheumatoid Arthritis with Major Adverse Cardiovascular Events Despite Normal Myocardial Perfusion Imaging
American Journal of Preventive Cardiology
A retrospective matched-cohort study found that rheumatoid arthritis was associated with higher rates of major adverse cardiovascular events even when myocardial perfusion imaging showed no ischemia. The findings highlight residual cardiovascular risk that a normal SPECT or PET perfusion study may not capture.
Evaluating the Quality of Cardiovascular Disease Information From AI Chatbots: A Comparative Study
PMID: 40821349
This comparative study evaluated the readability, quality, understandability, and actionability of four AI chatbots answering common questions about heart attacks, heart failure, and arrhythmias. Performance varied across the models and topics tested, underscoring the need to evaluate patient-facing cardiovascular information beyond factual accuracy alone.
Lipoprotein(a): A Review of Risk Factors, Measurements, and Novel Treatment Modalities
PMID: 38415744
This review examines lipoprotein(a), or Lp(a), as a cardiovascular risk factor, including the evidence linking it to atherosclerotic disease, challenges in measurement, and emerging treatment approaches. It brings together observational and genetic evidence to explain why Lp(a) matters in cardiovascular risk assessment.
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Occasional essays and notes as I learn, write, and build around medicine, prevention, and AI.
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